Characterising the function of niche-derived Neuregulin 1 in colorectal cancer [ 1/1/2021 - 12/31/2024 ]

Research Grant

Brief description Colorectal cancer affects thousands of Australians each year. A specialised cell population, named cancer stem cells, continuously produces new tumour cells. Defining mechanisms controlling the behaviour of these unique cells is critical to develop new drugs. We have identified that Neuregulin-1 is a key factor that enhances the action of cancer stem cells. We aim to study how colorectal cancer is mediated and whether targeting Neuregulin-1 is a promising therapeutic option.

Funding Amount $994,246

Funding Scheme Ideas Grants

Chief Investigator Dr Thierry Jarde

Notes Ideas Grants