Characterising and exploiting δ subunit-containing GABA-A receptors as novel targets for treating social disorders [ 2019 - ]

Research Grant

Brief description Our recent pilot data provides the first solid evidence that δGABAARs are involved in social behaviour and we have effectively targeted them pharmacologically to reduce social deficits in a rodent autism model. This project will: (1) thoroughly define the role of δ-GABAARs in social behaviour; (2) assess abnormal functioning of δ-GABAARs in a rodent model of autism; and (3) discover and develop new drugs targeting δ-GABAARs, potentially providing much needed drug candidates for social disorders.

Funding Amount $634,841.00

Funding Scheme Project Grants

Notes Standard Project Grant