Characterisation of T-cell Responses in Drug Hypersensitivity [ 2011 - 2013 ]

Research Grant

Researchers: Prof Elizabeth Phillips (Principal investigator) ,  A/Pr Michaela Lucas ,  Prof Simon Mallal

Brief description Drug hypersensitivity reactions (DIHS) are a catastrophic form of adverse drug reaction. This study will use the drug abacavir, a cause of drug hypersensitivity to examine the way certain immune cells react and determine whether responses to viruses that are persistent in our bodies play a role these development of these reactions. This will help inform the immunological basis of DIHS as well as new treatments and potential ways of identifying drugs likely to cause these reactions in the pre-marketing phase of drug development.

Funding Amount $AUD 306,338.00

Funding Scheme Project Grants

Notes Standard Project Grant