Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/114202]Researchers: Prof Eric Reynolds (Principal investigator)
Brief description This project involves the study of two proteins that associate with calcium and phosphate. Phosphophoryn is found in teeth and is responsible for the development of dentine in teeth. Osteopontin is a multi-functional protein found in a variety of tissues as well as in bone and in milk. Its functions in bone and milk are unknown although it is believed to be involved in bone remodelling. This project involves characterisation of these two proteins and their interactions with calcium phosphate mineral using a variety of techniques. The outcome will be an improved understanding of the design principles used by nature to engineer teeth and bone. The significance is the potential development of biocompatible apatite-based biomaterials for both tooth and bone.
Funding Amount $AUD 234,175.08
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 114202
- PURL : https://purl.org/au-research/grants/nhmrc/114202
