CHARACTERISATION OF A NOVEL REGULATOR OF PHOSPHOINOSITIDE 3-KINASE-MEDIATED CELL PROLIFERATION AND PLATELET SIGNALLING [ 2001 - 2003 ]

Research Grant

Researchers: Prof Harshal Nandurkar (Principal investigator) ,  Prof Christina Mitchell

Brief description Critical functions such as cell growth, cell death and metabolism, are tightly controlled by key proteins which respond to specific stimuli. Perturbation of this process may lead to uncontrolled growth and cancer. This project proposes to examine the potential of a novel protein (an enzyme) as a physiological regulator of cell growth. It is proposed that this enzyme may function as a brake in preventing the evolution of a cancerous state. We will also study the ability of the novel enzyme to influence other diverse functions, such as uptake of glucose, and blood clot initiation.

Funding Amount $AUD 500,091.80

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant