Characterisation of a newly-discovered, virulence-associated, protein secretion system of enteropathogenic E. coli [ 2009 - 2011 ]

Research Grant

Researchers: Prof Roy Robins-Browne (Principal investigator) ,  Dr Marija Tauschek ,  Prof Trevor Lithgow

Brief description The cell walls of bacteria act as a barrier to the export of any proteins they produce. We recently discovered a protein secretion system, which diarrhoea-causing strains of E. coli require to cause disease. The aim of this study is to characterise this secretory system, and discover how it functions and what it secretes. The knowledge obtained from this research will shed new light on how E. coli causes disease and could reveal novel methods to treat and prevent infections with this bacterium.

Funding Amount $AUD 582,149.03

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant