Characterisation of two new kinases in the Hippo tumour suppressor pathway [ 2014 - 2016 ]

Research Grant

Researchers: Prof Kieran Harvey (Principal investigator)

Brief description The Hippo pathway is a key regulator of tissue growth. It was first discovered in vinegar flies and plays a similar role in mammals. We aim to define the mechanism by which the Gish and Fray kinases control tissue growth by regulating the Hippo pathway. These studies will be performed in flies and mammalian cell culture. Our studies will shed light on how tissue growth is controlled, and have the potential to inform the way that we treat human cancers and tissue growth disorders.

Funding Amount $AUD 550,602.80

Funding Scheme Project Grants

Notes Standard Project Grant