grant

Characterisation of extracellular DNases of Pseudomonas aeruginosa and their contribution to disease [ 2008 - 2011 ]

Also known as: How the bacterium Pseudomonas aeruginosa causes disease

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/491130]

Researchers: A/Pr Cynthia Whitchurch (Principal investigator)

Brief description The bacterium Pseudomonas aeruginosa causes a number of serious diseases of humans particularly of immunocompromised patients. We have found that this bacterium secretes enzymes that have the ability to digest DNA. This proposal aims to work out how this bacterium uses these enzymes to infect human tissues and escape killing by immune cells. The results from this study will help to determine if these proteins may be used as targets for the development of new anti-infective drugs.

Funding Amount $AUD 418,516.81

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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