The characterisation of an essential regulator of pre-mRNA splicing required for germ cell function and male fertility [ 2015 - ]

Research Grant

Researchers: Prof Moira O'Bryan (Principal investigator) ,  Dr Duangporn Jamsai ,  Dr Robin Hobbs

Brief description The male germ line is a fantastic system within which to define processes of fundamental importance to cell biology and health broadly. Within this grant we will define the role of a poorly described RNA splicing factor in all of stem cell function (spermatogonia), meiosis (spermatocytes) and in the remarkable metamorphosis underlying spermatid maturation. This will be done using a range of phenotypic characterizations, CHIP and RNA Seq technologies and gene sequencing.

Funding Amount $1,076,799.00

Funding Scheme Project Grants

Notes Standard Project Grant