grant

Ceramide metabolism and ER stress in fatty-acid mediated destruction of pancreatic beta cells [ 2010 - 2012 ]

Also known as: Lipids and pancreatic beta cell death

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/596828]

Researchers: Prof Trevor Biden (Principal investigator)

Brief description The underlying cause of Type 2 diabetes is the failure of pancreatic beta cells to secrete sufficient insulin to overcome the insulin resistance that is associated with obesity. Beta cell failre is associated with both defective insulin secretion and loss of beta cell mass. This proposal focuses on the cellular mechanisms and stress pathways whereby too much fatty acid promotes beta cell death.

Funding Amount $AUD 549,092.56

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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