Cellular therapy for genetic liver disease exploiting induced pluripotent stem cells and liver progenitor cells [ 2012 - 2014 ]

Research Grant

Researchers: Prof Ian Alexander (Principal investigator) ,  Prof David Russell ,  Prof George Yeoh ,  Prof Patrick Tam

Brief description It has recently become possible to genetically reprogram mature cell types in the body to become stem cells and then redirect them to become any other cell type desired. This technology has immense, but as yet unrealised, diagnostic and therapeutic potential. In this project we seek to develop cellular therapies for metabolic liver disease. Specifically, we plan to generate liver cells from skin cells and to test the therapeutic effectiveness of these cells by curing liver disease in mice.

Funding Amount $AUD 797,185.62

Funding Scheme Project Grants

Notes Standard Project Grant