Cellular and Molecular Characterization of Erythroid Enucleation [ 2016 - 2018 ]

Research Grant

Researchers: Prof Patrick Humbert (Principal investigator)

Brief description A major challenge for transfusion medicine is the constant difficulties in obtaining enough supply of specific red blood cell (RBC) subtypes. In this proposal, we will identify the key steps of enucleation (extrusion of nucleus), a rate limiting process for the in vitro production of RBCs. A better understanding of this process will lead to improved strategies for the efficient and rapid production of self-generated RBCs for individual patient transfusion.

Funding Amount $AUD 690,725.23

Funding Scheme Project Grants

Notes Standard Project Grant