grant

Cell-selective deletion of brain AT1A receptors in hypertension: Effect on blood pressure, increased ROS production and inflammation. [ 2012 - 2015 ]

Also known as: AT1A receptor in hypertension

Funded by National Health and Medical Research Council
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1029396]

Researchers: Prof Andrew Allen (Principal investigator)

Brief description Angiotensin is important for normal regulation of blood pressure but is also involved in cardiovascular diseases. Interruption of angiotensin’s actions is a common treatment of these diseases. Functional deletion of angiotensin receptors decreases blood pressure. Surprisingly the site(s) in the body responsible for this decrease are not known. We will examine the role of angiotensin receptors in the brain in the control of blood pressure in health and in cardiovascular disease.

Funding Amount $AUD 578,268.15

Funding Scheme Project Grants

Notes Standard Project Grant

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Related Publications

  • Associated with Stimulation of Angiotensin Type 1A Receptors on Catecholaminergic Cells Contributes to Angiotensin-Dependent Hypertension
    URI : http://hdl.handle.net/11343/41978

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Subjects
Autonomic Nervous System | Cre/lox knockout mice | Medical and Health Sciences | Neurosciences | baroreceptor reflexes | blood pressure regulation | hypertension | lentivirus | sympathetic nervous system | transgenic mouse |
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