Cell cycle tracking of B cell differentiation and mutation [ 2014 - 2016 ]

Research Grant

Researchers: Dr Christopher Jolly (Principal investigator) ,  Dr Adam Cook

Brief description Antibody-mediated immunity to infectious diseases requires the proliferation of infection-specific antibody-producing B cells. The fate of responding B cells is linked to this proliferation according to a poorly understood division-based “map”. This project will track B cell fates in vivo using advanced imaging techniques. We will define differences between B cells from young versus old individuals that may explain why the effectiveness of the immune system declines with age.

Funding Amount $AUD 719,666.94

Funding Scheme Project Grants

Notes Standard Project Grant