grant

Cell biology of stress fractures: activation of remodelling at sites of non-union [ 2008 - 2012 ]

Also known as: Biology of stress fracture healing

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/511187]

Researchers: Prof Mark Forwood (Principal investigator) ,  Prof Gail Anderson

Brief description Stress fractures are debilitating injuries. We characterised a model of stress fractures in rat ulnae, learning that they heal by activated remodelling, that key genes are expressed in a temporal pattern, and that part of the fracture remains un-healed, similar to many clinical cases. Now, we will examine cell localisation of important genes necessary for remodelling, and test the efficacy of different growth factors to activate a healing response in the non-healed section of the fracture.

Funding Amount $AUD 493,817.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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