CD8 T cell regulation of humoral immune responses [ 2012 - 2014 ]

Research Grant

Researchers: A/Pr Cecile King (Principal investigator) ,  Prof Jonathan Sprent

Brief description Our bodies rely on the production of potent, or ‘high affinity’, antibodies to fight infection. We have found that antibody responses are unexpectedly boosted following the depletion of a specific subset of immune cells. This is especially true for B cells that are poor antibody producers. Our findings are likely to be relevant to (1) the design of vaccines to infectious agents that have important CTL and antibody components (e.g. HIV), (2) for the improved production of antibody for therapeutic use (e.g. cancer).

Funding Amount $AUD 601,712.52

Funding Scheme Project Grants

Notes Standard Project Grant