Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/566672]Researchers: Dr Brett Cromer (Principal investigator) , Prof Graham Lamb
Brief description Muscle chloride channels regulate how readily muscles are activated, particularly during muscle fatigue. Recently we have identified a feed-back mechanism linking chloride channel function to muscle acidosis and energy depletion, key factors in fatigue. Here we will investigate the molecular details of this mechanism and its role in muscle physiology and fatigue. This mechanism may present a future target for the treatment of myotonia, a condition where muscles are too readily activated.
Funding Amount $AUD 523,455.59
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 566672
- PURL : https://purl.org/au-research/grants/nhmrc/566672
