grant

The cardiomyocyte mineralocorticoid receptor plays a critical role in cardiac disease. [ 2011 - 2013 ]

Also known as: A pivitol role for the mineralocorticoid receptors in heart diesase.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1010034]

Researchers: Dr Morag Young (Principal investigator) ,  Prof Peter Fuller

Brief description Drugs that block the mineralocorticoid receptor (MR), which responds to adrenal hormones, protect against heart disease and hypertension. We have shown that this effect is in part due to MR blockade in heart muscle cells. This novel finding is being explored further to understand the precise role of the MR in heart muscle cells in normal physiology and in disease. An understanding of the role of the MR in different tissues will enable development of tissue specific treatments for heart disease.

Funding Amount $AUD 613,477.70

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857