Cardiac regeneration and heart disease [ 2011 - 2013 ]

Research Grant

Researchers: Prof Bob Graham (Principal investigator) ,  Dr Ming Li ,  Dr Siiri Iismaa

Brief description Heart muscle cells have little potential for regeneration, and after a heart attack or in response to chronic hypertension, they grow bigger, resulting in deterioration of function and heart failure. We have compelling evidence that the c-kit protein limits heart regeneration and function. We expect to demonstrate that c-kit inactivation can greatly improve heart regeneration and function after cardiac injury/stress. Our work will have major clinical significance for future heart failure treatment strategies.

Funding Amount $AUD 555,471.55

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant