Can efficient algal variants of the photosynthetic CO2-fixing enzyme, Rubisco, be folded and assembled in functional forms in higher-plant plastids? [ 2003-01-01 - 2005-12-31 ]

Research Grant

Researchers: Prof Thomas Andrews (Chief Investigator) ,  The Australian National University (Managed by)

Brief description Can efficient algal variants of the photosynthetic CO2-fixing enzyme, Rubisco, be folded and assembled in functional forms in higher-plant plastids? We have shown that it is possible to alter the photosynthetic phenotype of a plant predictably and profoundly by engineering the plastid genome to replace the plant's CO2-fixing enzyme, Rubisco, with a bacterial homolog. Thus it may be possible to replace the plant enzyme with more efficient algal Rubiscos that would allow plants to grow with less light, less water or less fertiliser. Before such desirable changes to the plant phenotype can be realised, some complex issues of modification, folding and assembly of Rubisco subunits need to be resolved. This proposal addresses them.

Funding Amount $495,000

Funding Scheme Discovery Projects

View this grant in the ARC Data Portal