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Calpeptin, and related candidates, for the treatment of Machado Joseph disease [ 2018 - 2021 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1146750]

Researchers: Dr Angela Laird (Principal investigator) ,  A/Pr Rohan Davis Dr Adam Walker Dr Albert Lee Dr Marco Morsch
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Brief description Machado Joseph Disease (MJD) is a neurodegenerative disease that causes impaired movement and progressive paralysis, leading to patient death. MJD is inherited within families, including a high number of Indigenous families of northeast Arnhem Land. We have identified a possible treatment for MJD that has positive effects on a small animal model of the disease (zebrafish carrying the human MJD gene). We plan to test this treatment further with the aim of developing a treatment for MJD patients.

Funding Amount $AUD 888,040.92

Funding Scheme Project Grants

Notes Standard Project Grant

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