[Cite as http://purl.org/au-research/grants/nhmrc/572516]
Prof Wallace Langdon
Dr Christine Thien
Brief description Acute myeloid leukaemia (AML) is a major health problem with only about one third of patients being cured. In addition therapies have changed little over the last 20 years. However there is optimism that with greater knowledge of the biochemical changes in AML that are caused by genetic mutations, more effective treatments will be developed. This project therefore aims to increase understanding of the biochemical interplay between two proteins called c-Cbl and Flt3 that are altered in AML.
Funding Amount $AUD 358,160.05
Funding Scheme NHMRC Project Grants
Standard Project Grant