Building mitochondrial Complex I, the first assembly of the cells powerplant. [ 2010 - ]

Research Grant

Researchers: Prof Michael Ryan (Principal investigator) ,  Dr Matthew McKenzie ,  Prof David Thorburn

Brief description Complex I is the first complex of the mitochondrial respiratory chain that is involved in producing most of the cell's energy. Mitochondria diseases occur ~1-5,000 live births with defects in Complex I being the most prevalent, often leading to death. Complex I defects have also been implicated in common disease including Parkinson s disease. This study will provide important new information into how Complex I is built and what goes wrong to cause disease.

Funding Amount $598,020.00

Funding Scheme Project Grants

Notes Standard Project Grant