Breaking malaria's lethal grip: Targeting the assembly of an adhesive complex on infected red blood cells [ 2015 - 2018 ]

Research Grant

Researchers: Prof Leann Tilley (Principal investigator) ,  Dr Matthew Dixon ,  Dr Paul Gilson ,  Prof Tania De Koning-Ward

Brief description The malaria parasite, Plasmodium falciparum, infects the red blood cells of its human victims. It causes them to stick to blood vessel walls in the brain, causing severe cerebral complications and death. Adhesion is mediated by a Velcro-like protein that is presented at the red blood cell surface. This project will fully elucidate the pathway for trafficking of the adhesion protein to the red blood cell surface with a view to finding new ways of interfering with malaria disease.

Funding Amount $AUD 817,426.71

Funding Scheme Project Grants

Notes Standard Project Grant