The brain as a therapeutic target for heart failure [ 2017 - 2020 ]

Research Grant

Researchers: Prof Clive May (Principal investigator) ,  Dr Song Yao ,  Prof Andrew Allen

Brief description In heart failure there is a large increase in sympathetic nerve activity to the heart that leads to damage to the heart and sudden death. We have shown that lesion of the area postrema, a brain nucleus that senses hormones in the blood, reduces nerve activity to the heart and, importantly, improves cardiac function. We aim to translate these findings into a treatment that can be used clinically, which our findings compellingly indicate should improve cardiac function in heart failure

Funding Amount $AUD 945,481.57

Funding Scheme Project Grants

Notes Standard Project Grant