Boosting mitochondria- a new approach for protecting the aging optic nerve in glaucoma [ 2012 - 2014 ]

Research Grant

Researchers: Prof Jonathan Crowston (Principal investigator) ,  A/Pr Ian Trounce ,  Prof Gregory Steinberg

Brief description Increasing age is a major risk factor for neurodegeneration. We have recently shown that subjecting mice to intermittent periods of fasting improves mitochondrial function in the retina and reverses age-related decline in optic nerve vulnerability to injury. This project now aims to investigate key molecular pathway for restoring mitochondria and from this attempts to find more palatable therapeutic strategies for protecting the optic nerve from injury.

Funding Amount $AUD 391,784.63

Funding Scheme Project Grants

Notes Standard Project Grant