grant

Boosting effectiveness of new vaccines for dengue ,HFMD and influenza by targeting vaccine antigens to Clec9A on dendritic cells. [ 2013 - 2015 ]

Also known as: Targeting dendritic cells to boost vaccines against dengue, HFMD and influenza.

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1056401]

Researchers: Prof Ken Shortman (Principal investigator) ,  A/Pr Mireille Lahoud ,  A/Pr Paul Macary ,  Dr Sylvie Alonso

Brief description Australian and Singapore laboratories will collaborate to develop improved vaccines against virus diseases, particularly Dengue, Hand Foot and Mouth Disease and Influenza. A novel technology will be used, the targeting of vaccines to a receptor on the surface of the dendritic cells that control immune responses. This will be used to boost responses to a series of vaccine candidates that are otherwise insufficiently immunogenic.

Funding Amount $AUD 396,332.54

Funding Scheme Targeted Calls

Notes A*STAR - Utilising Integrative Technologies to Combat Emerging Infectious Disease

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Applied Immunology (Incl. Antibody Engineering, Xenotransplantation and T-Cell Therapies) | Immunology | Medical and Health Sciences | adaptive immunity | antibody | cell surface receptor | dengue | emerging diseases | genomics | influenza | targeting | vaccines | virus |
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