Bone Fragility: The Neglected Role of Cortical Porosity [ 2009 - 2011 ]

Also known as: Contribution of Cortical Porosity to Bone Fragility

Research Grant

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Researchers: Prof Ego Seeman (Principal investigator) ,  Dr Karlis Gross Dr Roger Zebaze Prof Eleanor Mackie Prof Mark Knackstedt
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Brief description Cortical (outer shell) or compact bone constitutes 80% of the skeleton. It is not solid as implied by its name but made of inter-connected canals resembling a network of roads. We recently discovered that most of the bone loss with age occurs from these canals, not from t rabecular bone as currently believed. This suggests to know why and how bone breaks requires the study of the morphology of these canals and how they change with age. This is what we propose to do. It has never been done.

Funding Amount $AUD 620,381.24

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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