Body composition changes in cardiac cachexia: pathophysiology, quantification and approaches to therapy [ 2002 - 2005 ]

Research Grant

Researchers: Prof David Kaye (Principal investigator) ,  Dr John Power ,  Dr Markandeya Jois

Brief description Cachexia is weight loss and weakness caused by disease, or as a side effect of illness. Congestive heart failure is a common cardiovascular condition that is accompanied by high mortality (up to 50% over 2 years) and considerable suffering. People with congestive heart failure often develop cachexia. This project will explore the mechanisms responsible for the development of cachexia using an animal model of cardiac cachexia that the researchers have developed. It will be complemented by an examination of the effects of exercise on measures of cachexia in patients with congestive heart failure. The researchers believe that this study will supply valuable new information about the development of cachexia and lead to new therapies for this syndrome.

Funding Amount $AUD 120,000.00

Funding Scheme NHMRC Strategic Awards

Notes Palliative Care Research