grant

Bitopic ligands as a novel approach to G-protein-coupled receptor selectivity [ 2011 - 2013 ]

Also known as: Bitopic ligands at GPCRs

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1011920]

Researchers: Dr Jonathan Lane (Principal investigator)

Brief description This project will focus on two important types of brain proteins that have been implicated in various symptoms associated with schizophrenia. The aim is to exploit a new paradigm of drug action that we have discovered, whereby novel compounds can be utilized to simultaneously target multiples sites on these brain proteins, in an effort to discover new mechanisms that can promote more selective signalling and, ultimately, can be used to design safer and more effective medicines.

Funding Amount $AUD 540,356.57

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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