Bisphosphonate Treatment of Childhood Femoral Head Avascular Necrosis due to Perthes Disease [ 2010 - 2015 ]

Research Grant

Researchers: Prof Christopher Cowell (Principal investigator) ,  A/Pr Bruce Foster ,  A/Pr Craig Munns ,  Prof David Little ,  Prof Margaret Zacharin

Brief description Perthes disease (PD) occurs following loss of blood supply to the hip (femoral head). It is a severe childhood disorder with over 250 new cases per year in Australia. PD results in flattening of the normally round femoral head and painful arthritis. The hip becomes flat because the bone is eaten by cells called osteoclasts. We will test if a medicine aimed at stopping these osteoclasts can prevent hip flattening. This should decrease the risk of arthritis and the need for hip replacement.

Funding Amount $AUD 1,368,242.06

Funding Scheme Project Grants

Notes Standard Project Grant