grant

Biology of EGFR Mutations in Glioblastoma Multiforme [ 2011 - 2013 ]

Also known as: How mutations in a pivotal protein receptor contribute to the growth and development of brain cancer.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1012020]

Researchers: Prof Terrance Johns (Principal investigator)

Brief description The epidermal growth factor receptor (EGFR) is a protein that has a critical role in the development of normal cells. In glioma, the most lethal of the brain cancers, the EGFR is altered. These alterations result in uncontrolled activation of the EGFR, causing signals that promote the growth and survival of brain cancer. This grant seeks to understand the nature of the signals mediated by the altered EGFR, in turn helping us develop better therapeutics for the treatment of this deadly cancer.

Funding Amount $AUD 287,445.24

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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