Biochemical and structural analysis of virus-host interactions during HIV-1 assembly [ 2009 - 2011 ]

Research Grant

Researchers: Prof Johnson Mak (Principal investigator) ,  Dr Marcel Hijnen

Brief description HIV Gag is the most important protein to direct the formation of infectious HIV. Researchers everywhere have had significant difficulty to generate full length HIV Gag for biochemical and structural analysis. We have since developed a novel way to prepare large amount of HIV Gag, and this project will take advantage of our discovery to determine the biochemical and the structural features of HIV Gag, ultimately, for the development of novel therapeutics through rational drug design.

Funding Amount $AUD 337,171.54

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant