The bHLH transcription factor LYL1 in normal and leukemic hematopoiesis [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr David Curtis (Principal investigator) ,  A/Pr Matthew Mccormack ,  Prof John Pimanda

Brief description This project aims to understand how two closely related genes, called SCL and LYL1, work together to control the production of normal red blood cells and when abnormally expressed, cause cancer of the white blood cells. We will specifcially examine how LYL1 causes a specific type of leukemia in children and determine blocking the function of LYL1 will be a useful way to kill leukemia cells.

Funding Amount $AUD 520,945.59

Funding Scheme Project Grants

Notes Standard Project Grant