How do BET bromodomain proteins regulate gene expression? [ 2018 - 2020 ]

Research Grant

Researchers: Prof Joel Mackay (Principal investigator) ,  Dr Ben Capuano ,  Prof Gerd Blobel

Brief description This project is aimed at defining the biochemical mechanisms of action of a class of gene regulatory proteins (BET proteins) that are currently considered to be exciting drug targets for a range of diseases, predominantly cancer. A better understanding of the means by which BET proteins regulate gene expression will be important for the rational design and application of drugs that selectively target the proteins.

Funding Amount $AUD 586,791.65

Funding Scheme Project Grants

Notes Standard Project Grant