Bcl-2 proteins in tumourigenesis [ 2013 - ]

Research Grant

Researchers: Dr Erinna Lee (Principal investigator)

Brief description Cell survival and death are controlled by two processes known as apoptosis and autophagy. Apoptosis eliminates damaged cells whereas autophagy gets rid of faulty components in the cell. The Bcl-2 proteins regulate both processes. It is well established that dysfunctional Bcl-2 regulation leads to cancer. In this project, we aim to investigate if deregulated Bcl-2 control of autophagy also has a key role in cancer progression and to obtain a molecular picture of how this control is exerted.

Funding Amount $415,041.00

Funding Scheme Project Grants

Notes New Investigator Grant