The axis of Bcl-2, plasmacytoid DCs and lupus as a basis for therapy [ 2016 - 2018 ]

Research Grant

Researchers: Prof Andrew Lew (Principal investigator) ,  Dr Yifan Zhan ,  Prof Eric Morand

Brief description Systemic lupus erythematosus (SLE) affects 1 in 1000 Australians, mostly women. Here the immune system goes awry and makes antibodies against the body’s own components including the body’s DNA. This leads to damage to many parts of the body including kidneys, joints, brain and heart. It is incurable. A particular immune cell controls the development of this disease and we have found this cell is selectively killed by an inexpensive drug, which we hope will be a better way of treating SLE.

Funding Amount $AUD 732,299.99

Funding Scheme Project Grants

Notes Standard Project Grant