Attenuating severe infections in chronic inflammatory diseases through modulation of transforming growth factor-? activity [ 2017 - 2020 ]

Research Grant

Researchers: Prof Philip Bardin (Principal investigator) ,  Dr Michael Gantier ,  Prof Katherine Loveland

Brief description Asthma and chronic obstructive pulmonary disease (COPD) are characterised by enhanced TGF? expression, which is accompanied by susceptibility to recurrent viral and bacterial infections. Such infections exacerbate lung inflammation in these patients, generally requiring emergency department treatment. This project proposes to clarify the therapeutic potential of TGF? inhibitors to reduce the impact of viral infections in patients with COPD and asthma.

Funding Amount $AUD 626,836.14

Funding Scheme Project Grants

Notes Standard Project Grant