ATP release from gastrointestinal epithelium: A potential target for the treatment of slow transient constipation [ 2013 - 2016 ]

Research Grant

Researchers: A/Pr Lu Liu (Principal investigator) ,  A/Pr Shaun Sandow ,  Dr Paul Bertrand

Brief description Slow transit constipation (STC) is a severe condition of the colon, almost exclusively affecting reproductive age women with no effective treatment. We recently found an association between STC and defects in connexin proteins in the large intestine. We aim to reveal the role of connexins and female hormones in the maintenance of normal intestinal function and their involvement in STC. The study will provide completely new perspectives in the understanding of the functional bowel disorders.

Funding Amount $AUD 317,775.10

Funding Scheme Project Grants

Notes Standard Project Grant