grant

ATM Activation and its functional Importance in DNA damage response [ 2009 - 2011 ]

Also known as: Activation of the protein kinase ATM

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/569591]

Researchers: Prof Martin Lavin (Principal investigator) ,  Dr Mark Graham ,  Dr Sergei Kozlov

Brief description ATM is the protein deficient in the human genetic disorder ataxia-telangiectasia (A-T). This syndrome is characterised by neurodegeneration and increased risk of cancer. ATM recognises damage in DNA and facilitates its repair to minimize the risk of genetic defects. The project is designed to investigate the mechanism of activation of ATM. This information is important to understand the role of ATM in preventing cancer.

Funding Amount $AUD 555,541.19

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Help

Related Organisations

Related People

Subjects
270199 | Ataxia telangiectasia | Biochemistry and molecular biology | Cancer and Related Disorders | Cerebellar disorder | Chromosomal Disorders | Cre-lox knockin mice | DNA damage | Genetic Defect | Phosphorylation | Radiation Biology |
Identifiers
Viewed: [[ro.stat.viewed]]
Saved to MyRDA Save to MyRDA