[Cite as http://purl.org/au-research/grants/nhmrc/526615]
Prof Dmitri Sviridov
Prof Brian Spratt
Prof Michael Bukrinsky
Brief description Atherosclerosis is an underlying cause of majority of cardiovascular diseases. The key element in the pathogenesis of atherosclerosis is impairment of cholesterol metabolism. Current treatment reduces cardiovascular disease by 30-40%, but the remaining risk is unacceptably high. A new idea how to treat atherosclerosis came from unexpected source, HIV infection. We propose to investigate how HIV causes atherosclerosis and if similar mechanisms are involved in common atherosclerosis.
Funding Amount $AUD 379,418.35
Funding Scheme NHMRC Project Grants
Standard Project Grant