Association between obesity, TGFb, thrombospondin and small abdominal aortic aneurysm progression. [ 2009 - 2013 ]

Research Grant

Researchers: Prof Jonathan Golledge (Principal investigator) ,  A/Pr Catherine Rush ,  Prof Jurg Ott ,  Prof Paul Norman ,  Prof Philip Walker
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Brief description Abdominal aortic aneurysm (AAA) is an important cause of mortality in middle aged and elderly Australians. The incidence of AAA continues to increase despite improvements in the medical management of atherosclerosis. We postulate that obesity is important in the progression of AAA. In a community screening study we found that waist-hip ratio was independently associated with AAA. In this project we investigate the mechanisms underlying this association between obesity and AAA.

Funding Amount $AUD 514,777.04

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant