Assembly of Mitochondrial Respiratory Chain Complexes and their Defects Associated with Disease. [ 2009 - 2012 ]

Research Grant

Researchers: Dr Matthew Mckenzie (Principal investigator)

Brief description Mitochondrial “respiratory chain complexes are multi-subunit assemblies that function to produce most of our cellular energy. Defects in the assembly of these complexes can result in mitochondrial disease, including infant death. The assembly of the respiratory complexes is a complicated procedure and the mechanisms involved in disease remain elusive. This work will aid in our understanding of how these protein complexes are built and how defects in their assembly can cause disease.

Funding Amount $AUD 413,431.00

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF