ARC Future Fellowships - Grant ID: FT160100267 [ 2017-02-01 - 2021-06-01 ]

Research Grant

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Researchers: Prof Frank Gruetzner (Future Fellowship)

Brief description The birth and death of mammalian sex chromosomes. This project aims to unravel the molecular mechanisms that underlie the transition from autosome to sex chromosome and progressive sex chromosome differentiation in mammals. Monotremes are the only mammalian species with a sex chromosome system that consists of ten sex chromosomes in platypus and nine in echidna. This project will analyse the genetic and epigenetic composition and organisation of the monotreme autosomes that evolved into sex chromosomes in other mammals and compare individual platypus and echidna sex chromosomes to discover how sex chromosomes come to be, differentiate and ultimately are replaced by new sex chromosomes.

Funding Amount $929,464

Funding Scheme ARC Future Fellowships

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