Apoptosis and Stem/Progenitor Cells in the Development and Treatment of Cancer [ 2017 - ]

Research Grant

Researchers: Prof Andreas Strasser (Principal investigator) ,  A/Pr Guillaume Lessene ,  Dr Philippe Bouillet ,  Dr Ruth Kluck ,  Prof David Huang
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Brief description To improve cancer therapy, we are studying two cancer hallmarks. The first is excessive cell survival. To combat this, we are developing drugs with commercial partners that directly activate the cell's death machinery. The second hallmark is inexorable proliferation, akin to that of stem cells, which can generate entire tissues, as we showed for the breast. ‘Rogue’ stem-like cells may initiate certain cancers. We hope to advance cancer therapy by identifying such cells and drugs that kill them.

Funding Amount $21,809,605.00

Funding Scheme Programs

Notes Program Grant