Apoptosis and Stem Cells in Cancer Development and Therapy [ 2012 - 2016 ]

Research Grant

Researchers: Prof Jerry Adams (Principal investigator) ,  Dr Philippe Bouillet ,  Dr Ruth Kluck ,  Prof Andreas Strasser ,  Prof David Huang
View all 11 related researchers

Brief description To improve cancer therapy, we are studying two cancer hallmarks: enhanced cell survival and stem cell-like behaviour. As we discovered, cell death is often blocked in cancer cells. Hence, we are attempting to develop drugs that flip the natural ‘cell death switch’. Stem cells are rare cells that generate entire tissues, as we showed for the breast. Certain cancers may be driven by ‘rogue’ stem cells. If so, eradication of these rare cells within the bulk tumour may require novel therapies.

Funding Amount $AUD 22,852,197.19

Funding Scheme Program Grants

Notes Program Grant