Antioxidant enzymes counter reactive oxygen species from steroidogenic cytochrome P450 enzymes in the ovary to limit aneuploidy of embryos [ 2018 - ]

Research Grant

Researchers: Prof Raymond Rodgers (Principal investigator) ,  A/Pr Elizabeth New ,  Prof Hugh Harris

Brief description Many birth defects are due to damage sustained by the eggs before ovulation. Aging allows more damage, hence the advice to have babies earlier in life. However, we believe we have identified a source of damage that happens during late development of the follicle in the weeks before ovulation. Proving this will enable us define when an egg is most at risk of damage and to devise strategies to lower the risk.

Funding Amount $536,978.00

Funding Scheme Project Grants

Notes Standard Project Grant