Antibodies to the invasion ligand EBA175 and protection from Plasmodium falciparum malaria [ 2012 - 2016 ]

Research Grant

Researchers: Dr Jack Richards (Principal investigator)

Brief description Malaria causes disease and death by invading into human red blood cells and it achieves this by using specific parasite proteins. One of these, erythrocyte binding antigen 175 (EBA175), is especially important and parasites have evolved different versions of the protein. This project seeks to understand the importance of these different EBA175 variants in evading antibody responses. This has important implications in understanding natural immunity but also for future vaccine development.

Funding Amount $AUD 407,792.17

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF