The anti-inflammatory role of collagen IV in asthma [ 2009 - 2011 ]

Research Grant

Researchers: A/Pr Janette Burgess (Principal investigator) ,  A/Pr Brian Oliver ,  Dr Markus Weckmann

Brief description We have discovered that a protein, tumstatin, is missing from the lungs of people with asthma. We now have exciting data showing, for the first time, that tumstatin can stop inflammation. If tumstatin is part of the system that normally limits inflammation in the lungs its absence in asthma may be critical. In this grant we will discover how tumstatin works to block inflammation and why it is absent in asthma. Our studies will provide vital information about the role of tumstatin in the airways.

Funding Amount $AUD 317,076.25

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant