Annexin-A1 Agonists Rescue Cardiac Contractile Function After Myocardial Infarction [ 2013 - 2015 ]

Research Grant

Researchers: Prof Rebecca Ritchie (Principal investigator) ,  Dr Xiao-Ming Gao ,  Dr Yuan Yang

Brief description Myocardial infarction (or heart attack, a result of reduced coronary blood flow) and subsequent heart failure are the major cause of death in Western societies; this is expanding to all corners of the globe. New treatments for heart attack are thus essential. We have discovered that the natural hormone annexin-A1 rescues heart muscle function over the short-term, and propose that drugs based on annexin-A1 will prevent cardiac dysfunction of heart muscle up to several weeks after heart attack.

Funding Amount $AUD 621,419.38

Funding Scheme Project Grants

Notes Standard Project Grant